Remodelling of RNA structures by proteins such as the DEAD-box (DDX) RNA helicases regulates gene expression at various stages. The budding yeast helicase Dhh1 and its human counterpart DDX6 are known ...

Identifying functional effects of noncoding variants is a major challenge in human genetics. To predict the noncoding-variant effects de novo from sequence, we ...

A DNA sequence code critical to our understanding of how human genes are turned on and off has just been unlocked by a team of scientists. Molecular biologists refer to this code as the “human ...

Superimposed on the genetic sequences coding for amino acids is a second genetic code. This second genetic code, which makes use of dual-use codons, or duons, specifies how genes are controlled. The ...

AMSTERDAM--(BUSINESS WIRE)--Annogen, the Amsterdam based biotech company behind the SuRE™ technology for the functional annotation of the non-coding part of the genome, today announced it has begun a ...

The nucleotide sequences coding for murine complement component C3 have been determined from a cloned genomic DNA fragment and several overlapping cloned complementary DNA fragments. The amino acid ...

Gene Cloning and Protein Expression in Insect Cells Is Faciliatated by New Methodologies Since the pioneering interferon expression studies conducted in the early 1980s, baculovirus-based expression ...